It's possible, but you might have to turn down some setttings on your mac for WoW. Although I don't understand why you can't do them one after the other, as they seem unrelated. I'm expecting you will struggle with doing both at the same time, unless you can use your eyes independently...Anyway, yes you should be able to, but perhaps a Mac Pro might be better suited to your needs. If the iMac is all your budget will stretch to, it should do the job. Will try it out when I get mine.