Noting this is a very early incarnation lacking menus, footer and other nav elements, so far...
I hate to say this, but I'm not a fan of this layout and agree a lack of a grid is a root cause as the other user noted in their comment. I'm not talking about the graphics (just remember to use CSS when possible so you reduce bandwidth and load time) or necessarily the colors, either, in this response.
I'm referring to the overall theme and layout choice. To me, it's like a bunch of cards posted on a bulletin board, all those content blocks in the two wells and the main block below the logo. I get the vibe someone created each block elsewhere then slapped some glue on the back and stuck them in there somewhat randomly. This might be because the contrast is so high and the colors so inconsistent. I do not sense a clarity in design other than one thing --- nice rounded corners for all blocks (which again, should be done in CSS).
Maybe that block below the header should span 100%, or be designed slightly differently or blended into the background better?
Of course with your radio station you are doing lots of promotions, showing off sponsors and such so I might be completely wrong. So I'm hesitate to say something like you're way off track or clumsy in design.
Based on your placeholder content maybe consider putting the promo stuff on the left side and the news and twitter stuff on the right, remember in web design and especially mobile device viewing, top left and left to right determines the most valuable real estate on the screen.
I'm sorry if this is not what you expected, I won't bug you on the little details because they'll get worked out in time. And this is only one man's opinion. I am interested too in what others have to say as I am on the fence a bit considering your business type, branding and purpose of the site.