i've NEVER used the dock (always seemed intrusive on a 13" macbook pro). for a long time, i used a custom prefpane called "dock gone". now, in mavericks, just this:
defaults write com.apple.dock autohide-delay -float 9999999; killall Dock
it hides the dock for a long time (9999999 seconds); if i need to see the dock, i hit Command-Option-D, same to hide it again. (you can always redo the command with a small number to bring back the original hide length).
i use launchpad to open apps (or spotlight search); mail unread menu gives me a menu icon when there's new mail. Command-Tab to scroll thru open apps...
and i work 'semi-fullscreen' in most apps (i.e. window dragged up to the menubar...so that THAT is always visible).
not for everyone, but works for me...