Best way to take notes on a PDF?

I ran into a similar issue a few weeks ago on a business document from a client. As far as I can remember, the Help section (in the menu bar when you open an Adobe .pdf document) will explain that to "edit" or "comment" on a document 1 or 2 things to be in place: (1) the author/owner of the document must have already authorized such use, and (2) you must have the full Adobe Acrobat package, not just Adobe reader. Check the Help section mentioned above and you'll find a URL to the software you need to download. I don't remember is there was a fee involved or not.

Hopefully, another MR'er will come along later with either a workaround or better info. ;-)

Give this a try. I haven't used it firsthand but looks like it might do what you need.

http://www.smileonmymac.com/PDFpen/features.html

This is almost a necro-thread, but the new and improved Preview from OsX 10.6 supports highlighting, notes, arrows, and many more features.

Try it yourself! Works great for me, no more printing!