it is a difference but ..overall the base imac model it is a powerful machine but a little help from fusion drive will be a must.
When you run an app will be faster thnx to fusion drive, when you run graphic will run smoother thnx to the 640M, and the quad core i5 processors are indeed a power house.. i think this machine don't need 8 GB RAM, with 4 should be more that enough 🙂