I don't know if there's an automated way to do that besides recording a formula being entered to convert to the row/column relative format. But you can manually code it.
Range("A1").Value ="Something"
Can turn into Cells(row#,col#) = "Something". You can do math inside there so if you want three rows over and one cell down you could do Cells(row() + 3, col# - 1) = "Something".
Hope that helps!