Not being able to close tabs in Safari on iPad2 has been driving me crazy! My father has complained about this for the past two months, since he got the iPad2 for his 80th birthday. We thought it was just him/his fingers maybe unsteady. Then I got an iPad2 for Xmas and have the same problem. Oddly, I discovered by mistake, if you tap just to the left of the "x" the tab will close. It seems like I'm tapping the edge of the tab to the left of the tab I want to close if that makes sense. Try it, it works! I don't know why this is "off" and tapping directly on the "x" doesn't work??? I googled this problem and I assume it's not very common because I really couldn't find anything on it. So I was happy to see this post and be able to respond