I played HoN for a few month but switched to Dota 2. I think the biggest advantage for Dota is the much bigger community. HoN is faster then Dota but i prefer the Dota interface and style.
I tried to play HoN but as the right-click was missing I could not move a muscle in the game. How do you activate the right click anyway?
Also my 10 years old Mac bought on ebay was to weak for the grafics