Handbrake is the best for ENCODING movies, but not quite the best for ripping them. If your doing a large amount of DVD's then it would be better to use a combo of a ripper, encoder and tagger. Plus you can do them in "batches" which is much more time efficient.
Personally I use RipIt + Handbrake + Identify = iTunes compatible movies with artwork and meta data all embedded in the movie file.
Use RipIt to rip the movies off the dvd's, then you can set Handbrake up with the queue to run through all the rips at night and depeninding on the computer and how many your doing they'll be done in the morning. Then us Identify to tag them all and add to iTunes.