Best way of speeding your mac...suggestions?

i read some blogs about keeping your mac on speeding up is to know what programs running on you computer close other unnecessary apps and monitor ur activity monitor but i just wanna know on this:

5. Delete unused preference panes. Every now and then we download programs that install preference panes, and then forget all about them. The real problem? Lot’s of these will load in the background at startup. Luckily it should be as easy as a right click to remove. If it’s not you can always manually delete them by going to / Library / PreferencePanes.
A lot of this is probably common sense, but it never hurts to see it spelled out. What tips and tricks have you found help you get the best performance out of your Mac?

Should i empty all files in this folder?

blueroom said:

Aside from an SSD (load times are sped up) just sell your old Mac and buy a faster newer Mac.

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uhmm my imac still be good and satisfied because still new its more than 1 year yet just wanna ask any comments on this "5. Delete unused preference panes. Every now and then we download programs that install preference panes, and then forget all about them. The real problem? Lot’s of these will load in the background at startup. Luckily it should be as easy as a right click to remove. If it’s not you can always manually delete them by going to / Library / PreferencePanes.
A lot of this is probably common sense, but it never hurts to see it spelled out. What tips and tricks have you found help you get the best performance out of your Mac?"

if i could leaser down those apps running on the background which is not necessary

oh yeah wrong folder hehehe sorry i select the "preferences" instead of "PreferencePanes"