for straight up performance probably flight simulator would be a choice because its not a new simulator its pretty old now so the newer hardware can run it with no problems, on the other hand x-plane 10 is new and I have it installed on my iMac same specs as yours and I can run at 40-60 fps with the textures at extreme res, full screen native res, 8xAA, 4xAnisotropic and all other settings default which looks pretty good.
Don't even bother trying to run at all max its well known there isn't a computer that can run x-plane 10 all maxed with good frame rates, I don't think its optimized for multiple gpu's either, I mean todays top hardware has problems running X-plane 9 all maxed so you get my point, of course it might be that the software needs optimizing.
In my humble opinion if your looking for the better simulator I vote for x-plane the aircraft behave more realistic, although I have my frustrations when using weather to simulate crosswinds its not very realistic on that part, I can say this because I am a pilot, if your just looking for some sim fun then either one is fine, just please don't get Microsoft Flight thats a joke.