Check your system log for any messages from NVIDIA or NVDA.
Check to see if you are getting acceleration. A tell-tale sign is if you normally have a translucent menu bar but it's solid grey, but safer would be to get an application like the "OpenGL Extensions Viewer" from the Mac App Store and confirm that the NVIDIA driver is running.
Hi, I downloaded the application, here's the report:
Renderer: NVIDIA GeForce GTX 680 OpenGL Engine
Vendor: NVIDIA Corporation
Memory: 2048 MB
Version: 3.2 NVIDIA-8.14.11 313.01.02f01
Device: MacPro5,1
Shading language version: 1.50
Max texture size: 16384 x 16384
Max vertex texture image units: 16
Max texture image units: 16
Max geometry texture units: 16
Max anisotropic filtering value: 16
Max viewport size: 16384 x 16384
Max Viewports: 16
Max Clip Distances: 8
Max samples: 8
Extensions: 19
GL_APPLE_client_storage
GL_APPLE_container_object_shareable
GL_APPLE_object_purgeable
GL_APPLE_rgb_422
GL_APPLE_row_bytes
GL_APPLE_texture_range
GL_ARB_explicit_attrib_location
GL_ARB_instanced_arrays
GL_ARB_occlusion_query2
GL_ARB_separate_shader_objects
GL_ARB_shader_bit_encoding
GL_ARB_texture_swizzle
GL_ARB_timer_query
GL_ATI_texture_mirror_once
GL_EXT_depth_bounds_test
GL_EXT_texture_compression_s3tc
GL_EXT_texture_filter_anisotropic
GL_EXT_texture_mirror_clamp
GL_EXT_texture_sRGB_decode
Core features
v3.0 (100 % - 23/23)
v3.1 (100 % - 8/8)
v3.2 (100 % - 10/10)
v3.3 (50 % - 5/10)
v4.0 (0 % - 0/14)
v4.1 (14 % - 1/7)
v4.2 (0 % - 0/12)
v4.3 (0 % - 0/1)
OpenGL driver version check (Current: 3.2 NVIDIA-8.14.11 313.01.02f01, Latest known: 3.2 NVIDIA-8.14.11 313.01.02f01):
Latest version of display drivers found
According the database, you are running the latest display drivers for your video card.
Few texture units found
This may slow down some applications using fragment programs or extensive texture mapping.
Extension verification: