Having the same issue, it is very annoying. I had this issue about 2 years ago with the then new Thunderbolt display, Apple released an update to fix it (which took several weeks...)
Now with Mavericks, the exact same bug is happening. Massive delay when changing volume, and when playing almost any audio, after a few seconds the speakers in the Thunderbolt display start crackling and have severe static and distortion. This is most frustrating, as I thought the bug was fixed, and this is a $1,000 monitor! Hoping for a fix soon, this is really unacceptable...