Won't run in Ultra, if you define "Ultra" as "pretty much maxed out everything". Then again, even a Titan struggles to maintain 40FPS at 1440p:
http://www.tomshardware.com/reviews/battlefield-4-graphics-card-performance,3634-9.html
Anyway:
- Run the game at 1440p, not 1080p. Downscaling looks terrible on LCDs.
- High textures (4GB VRAM helps), moderate shadows, minimal AA (2x SMAA/MSAA), no deferred AA, etc.
- You can keep AA down as 1440p on 27" is fairly dense and jaggies aren't as noticeable.