U proberly could, but I really don`t understand why you would downgrade all the way down to 2.2.1? Why not just stick to 3.0?
Anyway try this:
1. Put the phone in DFU mode (Hold power button and home button for 15 seconds and then release power button and BUT KEEP HOLDING THE HOME BUTTON)
2. Restore 3.0 firmware (Click shift and restore and do a restore of this firmware iPhone2,1_3.0_7A341_Restore.ipsw)
3. When it finishes you will get an error. Click ok and exit iTunes.
4. After you got that error use QuickPwn-225 (
http://www.quickpwn.com/2009/01/offi...indowsmac.html). When you use quickpwn it will tell you to to hold the power and home button for 15 seonds. Then release both buttons and then hold the power button for 2 seconds.
5. You are done.
This is taken from a post there on Macrumors. And it worked for me downgradinf to 3.0.....