Is there a noticeable real-world drawback in booting a 2012 Mini with a USB 3.0 SSD vs. a Thunderbolt SSD? I've read some of the threads here on it, and it seems like most people booting off an external are emptying out a LaCie or the Buffalo Ministation and putting an SSD in there. But with USB 3.0, you can save a lot of money (and a Thunderbolt port if your drive only has one). And if your enclosure's chipset supports SATA III, it should still be plenty fast. Has anyone doing this with USB 3.0 noticed a finicky connection, too much CPU overhead, or anything else? I'm aware that there is slightly higher latency with USB 3.0, but is this really noticeable? I've also seen the thread with CPU throttling/crash, but that was a stress test. At the moment, I have an Intel 320 in one of the drive bays of a Mac Pro 1,1 which I use mostly for Photoshop work. I just don't want to take a step backwards in performance.