Well I have this problem on my iBook. At first I thought it was just my printer, but now I have it with my iPod. I plug anything in to the usb ports and it is connected by my ibook doesn't recognize anything I plugin. My iPod is sitting here on do not disconnect, but it doesn't show up on my desktop or in itunes. When I plug in my Epson printer and try to print, it wont connect to the printer, but the printer is on and the connection is good. They both work on any other computer in my house. I go into system profiler and when I click USB it just has the loading wheel going. That's all I get. The weird thing is that my mouse which is connected via the USB port does work.