I have a PB 15" 1.25 with an MX500. I like to use the MX500 on my desk but I'm getting some wierd issues from it. When I first login, the mouse speed is too fast, I have to go into the preferences and move it one notch then back and its back where I like it. I think this is complicated by SideTrack touchpad driver, but I don't know. Does anyone know if these complicate each other? This doesn't happen when I don't have the Logitech Control Center installed, but I need it so I can use the extra buttons on my mouse for back/forward when browsing etc.