It depends.
It really depends on your usage, since at this point the two browsers seem pretty much equal for regular usage. And yes, probably the benchmarks will show that one is better than the other, but unless you're a very heavy user, it won't matter as much.
It's pretty simple: if you use Safari on other iOS devices, Safari 6.0 can't be beat, especially with the tighter integration. If you use Chrome on your iOS devices or have an Android, then Chrome is the obvious answer.
And of course lastly, if you only use your Mac, then it depends on Extensions. Chrome destroys Safari on extensions, no contest. If you rely on extensions, stick with Chrome, because Safari's extensions list has barely grown over the past few years and very infrequent updates.
Also, I see some people saying that Chrome crashes all the time. There must be something malfunctioning with their computer, or a bad installation, since majority of people do not have such problems, myself included. If they did, Chrome wouldn't be so popular on Mac as it is today. Common sense.