I am interested in knowing how much people think that there is a significant quality in audio playback using higher end cans on a ipod. A lot of hardcore audiophiles claim that it's a waste of money playing a few hundred dollars for reduced sonic quality from an itunes download, etc. etc. Personally I can tell a significant different in the overall balance, high/low registers, etc. upgrading to my Shure E2C from the regular Ipod/Griffin EarJams setup. The Shures perform better. But looking at the Shure E5C or Bang Olaffsun or Bose makes me wonder whether the sonic quality dramatically increase. Or playing ipod music through a high end Bang Olaffsun or Denon system? Hi-Fi then? Wonder what people here believe (talking to audiophiles here)?