I recently did a clean install of High Sierra on my Mid-2015 iMac. I have noticed about 30% of the time after a restart or cold boot that the mouse point is missing. If I move the pointer around over screen objects I can see that the mouse is working but the actual pointer is missing (I can even click or drag). I have a graphics tablet connected and it does the same thing so it is not the physical mouse. I started having this issue before I installed the tablet so it isn't the drivers or anything else related to the tablet. The pointer will usually appear somewhere between 30 seconds to 5 minutes later if I do nothing. I have the screen saver hot corners enabled, and if I activate the screen saver the pointer is always displayed after the screen saver exits (this has been my quick fix). I have disabled all my startup items but still have the issue. I have done limited testing in a new user account and have not had the issue, but since it doesn't happen all the time I cant really say whether the alternate account has the problem or not. I usually just sleep the computer and the problem does not happen on wake, just startup. Anyone having this issue or have any ideas?