So this is a new one... I believe my computer self-updated the other day (I have automatic updates turned on) and I'm now running 10.14.5. Lately, when I wake the machine from sleeping, the mouse is responsive and I can swap between desktops, but none of the apps are responsive. Clicking does nothing. I can't access the apple menu to restart. Keyboard commands appear to work (I can access the task manager and I can use the keyboard to navigate amongst the items, but I can't click on anything.). The only thing that seems to remedy the issue is a hard restart using the physical power button. Any ideas? I'd love to not need a restart every time I take my computer between home and the office.