I did a backup from my ipad2 to itunes, then restored from that backup when i had my ipad pro. I had an exact duplicate. And it was super fast and painless.
I think backing up to your computer via iTunes is a more complete backup, AFAIK. Would advise that route over iCloud. Also, again AFAIK, if you opt to encrypt the iTunes backup, more of your app passwords and details are backed-up, making the transition far less cumbersome.
It's better to do an encrypted back up in iTunes and do a restore from their rather then use iCloud. It will generally be faster to restore too then using iCloud dependent on how much data you have on the iPad.