Thusfar, i have not been able to get either Real or WMP to function properly in Safari-- i just don't think the integration is ready yet. I keep a copy of IE around for stuff like that, if i need it...
i'm hoping very much for a new beta release that helps with these filetypes...
an interesting FYI, instead of each browser having it's own location for plugins in X (like it was in 9) now there's a folder for all web browser plugins-- makes switching browsers easier...
pnw