Usually go with AF but when shooting macros or if I'm in a situation where the AF isn't able to really work well, I use MF. Some of my older lenses are MF so of course there I have no choice. One of my cameras is off at Katz Eye Optics right now, being fitted with a special Katz Eye split-prism focusing screen which should be very useful in working with my manual lenses or with MF on my newer lenses.