Most of the time I one-hand the phone, so I started placing my most used apps along my thumb arc on each page. That helps avoid the long reach for stuff I use the most on ip5. It looks a little odd on the screen, but it's surprisingly effective.
Next group of most used goes in the next ring out from my arc and so on. As a lefty, my least used apps on each page wind up to the top and right of my thumb arc, and the bottom left.
The apps I generally need quickly/frequently go directly on the thumb arc on the home page: Camera, Shazaam, Settings, and the Craftsman Garage Door Opener.