I had a iPhone 6 and I ended up switching to a 6 Plus and haven't looked back. I think your mileage will vary and it depends on person to person, but for me it was a easy choice. The larger display for reading sites and media consumption is just absolutely great, and to contrary belief I don't find the 6 Plus to be terribly cumbersome. It's still a very thin device for its size, and with the right case on I don't have issues with it being slippery.
I do lose my "on the go" texting ability and just being able to pull out my phone all in one fluid motion to check things or make calls on it, but having the Plus I just find myself pausing for a second instead of doing it all in one motion, but it's a acceptable trade off for me.
There's many times though where I can still use the Plus with one hand for browsing sites and using apps, I find myself using reachability a lot and it's working well for me, I don't have massive hands either or anything, I'm only 5'10.
I don't wear skinny jeans, My clothing is just a tad on the baggy side so it does comfortably fit in my pocket, and at work I wear dress pants most of the time which have very deep pockets, above all else my phone usually rests on my desk at work most of the day (I have a office job). Same with home, usually rests on my desk or nightstand. Using it at home is absolutely no problem if I'm just chilling on my furniture and texting/browsing with two hands.
I also take the mammoth battery life over the 6 anyday too
YMMV, the choice was easy for me.