Hello, I had over 250 photos, and finally found a simple solution - use image capture.
If you have a mac, and IMAGE CAPTURE apple program should be installed, (mine automatically pops up when plug in my iphone), choose OPTIONS ---> "Delete items off camera after downloading" and voila - you have downloaded all the pics to the folder of your choice, and the pictures are then deleted off the iphone! No itunes synching necessary! Great when you are at a friends house too
That only works for photos on the CameraRoll