Nope, writes are horribly slow to SDHC cards, unless you start looking at UHS Class cards, and that's just talking about theoretical spec-type numbers, not real-world. Speaking theoretical only, and if you want decent write speeds, don't even bother with Class 10 or below. With Class 10, we're talking a maximum of 30MB/sec (albeit with a minimum rating of 10MB/sec). Also, some manufacturers are selling SDHC cards that they classify as UHS Class 1, but are merely Class 10 cards from a performance perspective, so buyer beware where those are concerned.
Still speaking theoretical performance here, and not feasibility of using in a MBP, if you want anything like a HDD with flash-based storage, without jumping to SSD, you probably need to look at Compact Flash or UHS Class 1 SDHC for now, which can get comparable performance to HDD's, but even then, it's only theoretical speeds. Speeds on paper. Real-world results will most definitely be slower. Cost per GB is still more expensive than a traditional HDD, too.
Don't get me wrong, I was all for the whole SDHC as additional storage idea when I tried it. I loved the idea of stuffing all my TV shows and movies onto a couple dozen SDHC cards and storing them like poker chips ... sounded great, but UHS cards were much too expensive at the time I checked into it, and Class 10 took much too long for my taste to fill up a 64GB card. They just aren't where they need to be in order to be used to replace HDDs. Real-world performance results were very unimpressive. Realistically, IMHO, they are only useful for storing media ... music, photos, and videos, but be prepared for a long haul when doing the initial copy of media onto them. Start the job, then go browse the net, go for lunch, or have a coffee or something.
I should probably add that I haven't bothered looking into SDXC yet, aside from looking at the specs. Specs for them, like the SDHC, are unimpressive. Don't expect to be coming close to the max transfer rate with those on writes. Just not comparable at all to modern HDD's. Maybe to HDD's 6 or 8 years ago, but not now. Compact Flash are still the king of them all on theoretical performance and capacity for now. They just fail on physical footprint compared to everything else out there.