Aluminum Unibody Macbook(Late 2008) Won't Boot New Hard Drive

[CheekySpoon]

I'm trying to upgrade my hard drive, but my macbook will not boot to the new hard drive. I have erased and cloned the hard drive about three times now. It won't boot while it is in the macbook and it won't boot from an external hard drive case. All I get to is the screen with the mac logo and the spinning wheel. I have made sure the drive is GUID formatted, but it still doesn't work. When I put the new drive in an external case and plug it into my macbook I can see and access everything on the drive. Can somebody please tell what I am doing wrong?

By the way the new drive is a WD 500gb Scorpio Blue.

 

[miles01110]

Did you format the drive first? What did you use to clone the drive?

 

[CheekySpoon]

Did you format the drive first? What did you use to clone the drive?

I formatted all three times using Disk Utility first and I have used SuperDuper and Carbon Copy Cloner.