I've mostly read people on here dismissing the importance of ECC RAM in the Mac Pro... I read an article that argues it is actually very worthwhile. I haven't really formed an opinion one way or the other 
http://lambda-diode.com/opinion/ecc-memory
PS: I have no affiliation with the author or site... just came across it on reddit and thought it would be of interest to most Mac Pro owners.
A system on Earth, at sea level, with 4 GB of RAM has a 96% percent chance of having a bit error in three days without ECC RAM. With ECC RAM, that goes down to 1.67e-10 or about one chance in six billions.
http://lambda-diode.com/opinion/ecc-memory
PS: I have no affiliation with the author or site... just came across it on reddit and thought it would be of interest to most Mac Pro owners.