Well, there is an application that can let you use your isight from anywhere in the world over the internet - unfortunately I can't remember the name, but I'll have a search in a minute to see if I can find it.
You could always set up an iChat conversation. If you tell me what you want to use it for, I could give a better suggestion.
EDIT: Check Periscope out. Also, Check out Security Spy, which seems more of a fit. This might also help.