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I wanna know is it big difference between 4GB and 6GB?
That completely depends on your usage, and will vary from one user to another. To determine if you can benefit from more RAM, launch Activity Monitor and click the System Memory tab at the bottom to check your page outs. Page outs are cumulative since your last restart, so the best way to check is to restart your computer and track page outs under your normal workload (the apps, browser pages and documents you normally would have open). If your page outs are significant (say 1GB or more) under normal use, you may benefit from more RAM. If your page outs are zero or very low during normal use, you probably won't see any performance improvement from adding RAM.

Mac OS X: Reading system memory usage in Activity Monitor
 
That completely depends on your usage, and will vary from one user to another. To determine if you can benefit from more RAM, launch Activity Monitor and click the System Memory tab at the bottom to check your page outs. Page outs are cumulative since your last restart, so the best way to check is to restart your computer and track page outs under your normal workload (the apps, browser pages and documents you normally would have open). If your page outs are significant (say 1GB or more) under normal use, you may benefit from more RAM. If your page outs are zero or very low during normal use, you probably won't see any performance improvement from adding RAM.

Mac OS X: Reading system memory usage in Activity Monitor

Thx for advice
 
For typical day to day web browsing and email, there won't be a big difference. The fact that you have to ask means you probably don't need the upgrade ;). That said, if you want to, then by all means do.
 
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