Yes, perfectly happy. June 2009 2.53GHz 15" MacBook Pro (stock). I do intend to upgrade the hard drive at some point; I agree with the previous post stating that 250GB can be constrictive. For me, the issue is a 100GB music library that I prefer to keep on the internal drive rather than on an external.
The lack of discrete graphics was not a concern for me because my type of usage simply doesn't require the discrete option. In addition, I had had several of the first generation of unibody Pros (all of which had the discrete card), most of which had flickering screens. There was some speculation online at the time that the dual-card setup might have had something to do with it. Maybe, maybe not, but I preferred not to take the chance since I didn't need the faster graphics anyway.
Typically running at the same time on my machine: Firefox, Adium, Skype, Evernote, SugarSync. Quicksilver, SnapNDrag and TextExpander in the background. Still excellent performance when I launch the more occasional apps: XCode, TextMate, iTerm, MacJournal, Mail, iCal, VMWare Fusion.
So, again, very satisfied. When prices come down I'll upgrade to 8GB RAM just because, and I will probably throw a 500GB hdd in there as soon as Snow Leopard is released and do a clean install.