Hey Alfredo,
i have a 15” MBP and use the following back-up strategy and have used this for the last 10 years.
I have two separate WD Mac Studio FireWire 800 external drives (Why FireWire?), that’s because I’m on a Mid 2012 MBP and that’s the fastest I could get.
I use one external drive for Time Machine backups and the second for Full + Incremental backups using CCC (Carbon Copy Cloner).
With that said, I have been running VMware that has a 100Gb VM partition hosting Windows 7 Professional and I’ve never had an issue with either.
CCC is also great for upgrading/cloning drives for instance, cloning current drive to a new SSD.
Hope this helps! 👍