Best way to enter addresses for labels?

[goofyY]

I am stuck entering a lot of physical addresses to make labels for a mass mailing. Am I better off doing a numbers spreadsheet or entering them into an address book?

The spread sheet seem like the way to go, do I use separate columns for each part of the address (street, city, state, zip) or group them together?

thanks

 

[dyt1983]

edit: to remove personally identifying information not relevant to thread.