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Swiss Gear is my vote. I know a lot of people like the Syngery backpack by them. My brother uses it. I like it as well but I was given a different Swiss Gear backpack for my birthday and I love it as well.

I say check out Swiss Gear. A lot of their backpacks are pretty neutral in coloring and I know quite a few professional who carry them around.
I know in my backpack it can carry a fair amount of stuff. I will put in my 15in laptop with all the power cords and then load it up with my textbooks for class for the day no problem with some room to spare.
 
I use a Karrimor Spectre 20 which I use for hillwalking, but inside the main compartment, there is a seperate pocket with elastic that holds a 15" MBP perfectly, while still providing alot of space infront of it.
 
I have a North Face backpack that use I for College. It is great for holding my mbp and books. It has a separate sleeve inside the main compartment I keep my laptop in.

You can look at something like this
 
I recommend the Crumpler Beer Back. It's a very big bag with lots of room and looks simple yet nice from behind.

crumpler-back-laptop-backpack.jpg
 
Anything DAKINE!

dakine.com

I've owned a couple backpacks, a couple duffles, and a luggage bag from them... top quality and prices are not bad.

8130-005_NETWORK_HERRBN4.jpg
 
I use an east pak floyd for my mbp15" and books. You can have about 2 decent sized books in the main pocket.

and i think it looks pretty cool

lots of different designs available too
 

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Swiss Gear is my vote. I know a lot of people like the Syngery backpack by them. My brother uses it. I like it as well but I was given a different Swiss Gear backpack for my birthday and I love it as well.

SwissGear is awesome! not only does it have a ton of space for your laptop and extra school related items, it is very comfortable on your back as well. It is pretty neat, however can be expensive.
 
I switch between my

Oakley AP 3.0
North Face Big Shot

The Big Shot doesn't have a separate laptop compartment but I use a sleeve do it doesn't matter for me really. The AP pack is good for your laptop and smaller items. The Northface can haul pretty much anything you got.
 
SwissGear is awesome! not only does it have a ton of space for your laptop and extra school related items, it is very comfortable on your back as well. It is pretty neat, however can be expensive.

Actually, relative to the rest of the recommendations, Swiss Gear backpacks are amongst the most value-priced you can get. I highly recommend them for both security of your laptop as well as the extra, often expandable middle compartment. Its great for extra gear.
 
I love my Incase backpack (it's there smaller design). Doesn't hold too much in the way of textbooks. About enough for a small binder and two medium size textbooks... and my Mac of course. Perfect for my schedule though.
 
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