To get a complete picture, launch Activity Monitor and change "My Processes" at the top to "All Processes", then click on the CPU column heading once or twice, so the arrow points downward (highest values on top). Then see what apps are using system resources.
Second, 200MB is trivial compared to the virtual memory available.
Third, when comparing any apps, look not just at memory usage, but CPU usage, as well.
Finally, the recommendation against Sophos is not about RAM or CPU usage or performance issues at all, but about the added vulnerability of running such an app with elevated privileges, as explained in the links I posted in post #6. There is no need to run any antivirus app all the time (or at all). ClamXav does a good job as a tool to periodically scan for malware, but it's not necessary to have it or any other AV app running all the time.