I've had this problem with the clicks not always registering on my MBP14. I have updated to the latest macOS 12.3 and still have this issue. I have tap to click turned on and when I click between different apps or sometimes even within the same app such as message.app, the clicks won't register. It takes several tries before it does, and sometimes I have to click out of the window and back into the app window for it to work. It's driving me insane! Does anyone know what the problem is?