Just yesterday I put a 240GB SSD in my MacBook 2,1 Intel Core 2 Duo 2.16 GHz. I also replaced the two stock 512MB RAM sticks with a 1GB and 2GB stick. I bought everything from Other Word Computing. They were great to deal with - I talked with a sales person who helped me decide what to order and then I talked with tech support after everything arrived with a few newbie questions.
Anyway, it's like a brand new machine - boots up in about 5 seconds compared with about 45 seconds before. Apps open almost instantaneously. I've heard about the TRIM issue but haven't researched it yet so I don't know much about it. So far though I'm thrilled with these upgrades.