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Without messing with adaptors, you could just get a FW800 enclosure. It's not as fast as eSATA, but way faster than USB2.0.
 
I agree with this statement.

Somebody PLEASE (apologies for the e-yelling) give me a link to a good enclosure w/firewire 800 which has a fann.....I can not find one anywhere ! I will be leaving mine on 24/7, with a 750GB HDD, so its going to need a fan...
 
If you really need to use eSATA you can purchase an eSATA ExpressCard to use with your MacBook Pro which should give you a total of two eSATA interface ports. I've seen them on the Apple Online Store.
 
Somebody PLEASE (apologies for the e-yelling) give me a link to a good enclosure w/firewire 800 which has a fann.....I can not find one anywhere ! I will be leaving mine on 24/7, with a 750GB HDD, so its going to need a fan...

Here. Results of a 30 second search. May not quite be what you're looking for.

Personally, I have 250GB and 1TB externals in aluminum enclosures without fans. I run them 24/7. After a couple hours of uninterrupted writing, they do get warm, but never hot.
 
I found this:
http://times.usefulinc.com/2007/01/17-sata-box
as an sata solution to external storage. I currently have an IcyBox with Fw800, SATA and USB (3-in-1) connected to a desktop PC direct to an SATA connection port (a little barbaric with a wire going in the side of the case but works fine), I believe the express card like the one mentioned would fit the bill in much the same way for eSATA on a MBP. any other cards recommended or are they all pretty generic. There is eSATA 2 available too...

p.s. always on external hdd's, is that ok? not better to turn on when needed?
 
Get a eSATA expresscard. Don't bother with the expensive ones. They all the same. Just make sure you get the 34 ones.
 
I was just about to respond with the bandwidth on the expresscard not being able to keep up, but I didn't realize it was 2.5Gbit/s...that's FAAST!
 
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