Nope. Those iMacs have more than enough graphics grunt to handle two monitors for just about anything that isn't so heavy duty you'd want to be running a Mac Pro anyway.
Even running lower-end graphics most computers Apple sells probably perform fine with two monitors, so long as you're not running Motion or something similarly extreme. My 4-year-old MBP had no issue driving its 17" built-in plus a 1080p TV, and I didn't even have any significant problems running an archaic G3 PowerBook with an internal and external monitor simultaneously.