I use a combination of Tweetie and Beak... Beak is in a very early technical preview... so is very, very, very buggy and has limited functionality... and where it cannot do stuff... I pull in Tweetie... I have bought Tweetie... with Grubers discount... and I think I paid about £9... I also have Twitteriffic... and am looking forward to Twitteriffic 3.0 being released..
Anyhows... you can get bogged down in Twitter Apps.. but hey!!!
J