A few things.
I have the Canon P-150M, the predecessor to the 215. Unfortunately, Canon apparently isn't gonna update the TWAIN drivers (they're 32 bit, not 64, and don't work with some applications). Nor are they gonna provide the Image Capture plugins. There's a workaround though; see here:
http://janegil.net/2014/01/twain-scanners-in-os-x-maverick/
I also use Graphic Converter 8, which can scan directly using the 32 bit TWAIN drivers. Or the Canon software, which works pretty well.
Consider an iPhone solution, though. There are some terrific scanning apps, like Jot Not. These days I rarely encounter documents that are conducive to sheet feed scanning. It's more likely odd shaped store receipts, cards, warranty cards, DMV documents, etc. It's sometimes easier to use an iPhone to get a good scan, and WAY cheaper. Send the scans to Evernote and use their PDF OCR feature, and even with some handwritten stuff you get a searchable PDF, really key for paperless storage.
Once I've got the receipts, and aside from Evernote, I prefer Yep for organizing the stuff, and use tags extensively. In fact, Leap is even better for this. By using tags you can also tie together receipts that would otherwise be difficult to store together; for instance, you can tag emails, photos, PDFs, and Word documents with a client name, even though each is in a different place in folders in the Finder.
Devonthink is also an excellent place to store scans, and other documents as well. It gives you option of either referencing those documents, or importing the actual files. And again you can lump stuff together, and use tags. I sometimes have the email, the scanned invoice, and even a archive of the web page I bought off of, all in one handy place.
Finally, it's a bit off the topic, but I like to save emails as PDFs for receipt purposes. I'm used to this as a lawyer, to have a more immutable archive of a document than an email stored on a server or locally. I use Email Archiver Pro for this, and it's great. Unlike a Save to PDF... it stores the header info in the PDF in a clever way, so it's viewable without getting in the way, and searchable.
Rob