I went through this same dilemma several months' back.
I found one app that actually did "file level" encryption.
BUT... it was
"pay-for" software, and my needs weren't great enough to entice me to buy it. I think its name began with "m"... don't even remember any more.
I also found this (haven't tried it):
https://itunes.apple.com/us/app/encrypto-secure-your-files/id935235287?mt=12
Having said that, if it's a Word file, you could use the password-protection offered by Word, as mentioned above (I don't use Word).
Beyond that, the easiest "road to small-potatoes encryption" on the Mac is to create a small disk image (5-10mb) and encrypt it with a password. Then, put whatever files you wish onto the encrypted disk image.
I did this and found a trick to quickly-access the file.
I -think- I did the following:
1. mount encrypted image
2. make an alias of the file that you will be accessing
3. put the alias wherever you wish for "quick access"
4. now UNmount the encrypted image.
After you do this, you can double-click the file alias, and the disk image (which its on) will present you with the password dialog. Enter the password, and the image will mount and the file will be opened.
5. When done working with the file, close it and UNmount the encrypted image.