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I personally love the Apple mighty mouse. It's a pain though, because I have to continually keep the scroll wheel clean. It's different than all the PC mice, but I like being different :p
 
It should work but you won't be able to program any buttons and the only thing that will work would be the scroll wheel and the mouse buttons. I have the Logitech VX Revolution and that's how mine reacted before I installed the Logitech Control Center.
 
I'm running a G5 and G15 on my mbp. The G keys on tha G15 oblivously doesnt work neither do the media keys (cept for the volume) And on the G5, everything words (thats including tha thumb button) Hope that helps :)
 
It does work. Im using that mouse right now. The scroll wheel works as well as the up and down/mute-unmute volume buttons. The rest of the buttons do nothing however.....
 
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