It's definitely subjective and it is also highly-dependent on the size of your display (e.g., a small Quad HD display can have a higher pixel density than a very large 4K display).
My best friend will say that anything less than 4K in macOS is worthless, especially since the anti-aliasing disabling (which you can partly re-enable, on a side note). He would call you crazy for considering anything less than 4K in 2020.
But I'm a huge QHD fan and absolutely love it on 24-25 inch screen sizes at shorter viewing distances in its native resolution...in that 24-25 inch size, you get a very respectable pixel density of around 120 PPI (which is better than a 40-inch 4K display). With QHD in the unscaled, native resolution, you get nicely sized icons/text without having to place a heavy load on the GPU (and I find that this, with laptops, benefits CPU performance.) There are a lot of options available for very reasonable prices, including models with high refresh rates, excellent color coverage, high-brightness, and HDR capability. Overall, I feel like QHD offers a nice sweet spot, and is a good choice for many professional as well as personal/entertainment applications.
But some others will say font size is too small on 24-25 inch QHD.
As we are in a COVID world and browsing in a store is no longer easy, you might want to consider selecting a QHD and 4K display you like and buying both (purchasing from somewhere with free returns, of course) and send the one back that you like less? This way you can see first hand how fonts look on each, what 4K scaling settings you like and how the system handles it, and how the system behaves from a performance standpoint with each.