Can't tell you about the keyboard, but the mouse will work ok. I use one with my iBook.However, there are no mac-specific drivers, so you only get the left and right buttons, and the basic scroll wheel. The other buttons won't work, neither will the tilting or clicking action on the scroll wheel.
(I think you can set some of these features up for use with Safari, but not for other apps - not sure as I haven't bothered to do this.)
For the extra it costs, I think it's worth getting bluetooth as a BTO, as you can then use it with a mobile phone, and even a Wacom tablet.