No, AFAIK.
You have a few options, though, depending on what you want.
1) Install it in the Applications directory of the user who will be using it, rather than in /applications -- then only they will be able to run it.
2) Convert users to limited accounts where you can specify what programs they can run
3) Put the application in a disk image file on your computer, and password protect the disk image. Then you will have to password in and mount the disk image to run the app. But users who do so could probably drag the app elsewhere and make a new copy that doesn't need a password.
There may be more...