All I know is what Apple says, which is no, here is what is in the article:
I have both a Mac and a PC. Will my iPod work on both?
Answer: No, iPod is specially configured for either Mac or PC. iPod for Mac comes in the HFS Plus file format which is optimized for performance and usability in Mac OS X and 9. iPod for Windows comes in the FAT32 file format which is optimized for performance and usability in Windows ME, 2000, and XP.
If you purchased an iPod for Windows, you can easily reformat it to work on your Mac by downloading the iPod for Mac Software Updater on the Apple Web site. Note that once it is reformatted, it will only work with Macs. You need Mac OS 9.2 or Mac OS X 10.1 or later to reformat an iPod for Windows into an iPod for Mac.
You cannot reformat an iPod for Mac to work with Windows.
Using the iPod for Mac on a PC, or using the iPod for Windows on a Mac, is not supported by Apple.
Question 9: Can I use my existing iPod for Mac on a PC, or my iPod for Windows on a Mac?
Answer: You can reformat your iPod for Windows into an iPod for Mac, but it is not possible to reconfigure your iPod for Mac to an iPod for Windows. This is because Windows does not support the HFS+ file system and therefore will not see the drive.
You can convert your iPod for Windows into an iPod for Mac by using the iPod for Mac Software Updater on the Apple website. Note that once it is reformatted, it will only work with Macs. You need Mac OS 9.2 or Mac OS X version 10.1 or later to reformat an iPod for Windows into an iPod for Mac.
Using the iPod for Mac on a PC, or using the iPod for Windows on a Mac, is not supported by Apple.
If you want to look for yourself it's at
http://docs.info.apple.com/article....alue=100&showSurvey=false&sessionID=anonymous|156536325